Olanzapine/samidorphan will reduce the extent or effect of hydromorphone by pharmacodynamic antagonism. Contraindicated. Samidorphan elicits opioid antagonistic effects and increases danger of precipitating acute opioid withdrawal in individuals depending on opioids. Reserve concomitant prescribing of such medications in individuals for whom other remedy solutions are insufficient. Li... https://seanr097vit5.p2blogs.com/profile